Photoplethysmography (PPG) is a non-invasive technique used to measure blood volume changes in the microvascular bed of tissue. This method involves using a light source and a photodetector to detect variations in light absorption, which correspond to the pulsatile nature of blood flow. The PPG signal primarily reflects the cardiac cycle, providing valuable information about heart rate and peripheral blood flow. In animal studies, particularly with rodents, PPG enables chronic, awake recordings that allow for continuous, non-invasive monitoring of physiological parameters such as oxygen saturation, heart rate, and breathing rate. This capability is essential for long-term studies without the need for invasive procedures.

The Mouse Ox System is a state-of-the-art PPG recording device tailored for use with rodents. This system offers high sensitivity and accuracy in detecting physiological signals, allowing for precise measurement of heart rate, breathing rate, and other vital parameters.